RARE INFECTIONS OF THE HEAD AND NECK: A CASE SERIES

Santosh, Dr. Neetha and Kiyani, Dr. Amber and Luqman, Dr. Uzair and Zulfiqar, Dr. Gulraiz and Farooq, Dr. Umar and Zaib, Dr. Nadia (2019) RARE INFECTIONS OF THE HEAD AND NECK: A CASE SERIES. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 128 (1). e60. ISSN 22124403

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Abstract

Protozoal, invasive fungal and mycobacterial infections in the head and neck region are exceedingly rare in the developed world. However, in developing countries, endemic infections may involve the oral mucosa or facial skin. Here we present three unusual infections involving these sites. Case 1: A 48-year-old male presented with difficulty in swallowing for a couple of months. Intraoral exam showed ulceration on the palate extending down to the oropharynx. Although a malignant diagnosis was favored initially, that was ruled out since a destructive lesion involving the left auricle and helix was also present. Histopathologically the case was diagnosed as leishmaniasis following identification of small oval organisms in macrophages which was confirmed with Giemsa stain. Case 2: A 38-year-old female presented with multiple nodules on the temporal skin that had been progressively enlarging over the past 2 years and hypo-pigmented skin patches. A prior biopsy was inconclusive. The repeat biopsy of the largest nodule showed presence of bright red colored bacilli on Fite staining confirming a diagnosis of leprosy. Case 3: A 19-yr-old male presented with a one year history of an extra-oral draining sinus after extraction of mandibular posteriors. Following a radiographic diagnosis of osteomyelitis, multiple courses of antibiotics were administered with no resolution and increase in the size of sequestrum. During surgical removal of sequestrum, a soft tissue mass was also noted in the vicinity. Sections from the necrotic bone and tumor-like mass showed chronic granulomatous inflammation along with septate hyphae, consistent with aspergillosis. All patients were referred to an infectious disease expert for further care. Each of this case enforces the need for histopathological awareness of infectious entities, so that appropriate treatment can be rendered.

Item Type: Article
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Health and Medical Sciences (FHMS) > Islamic International Dental College Islamabad
Depositing User: Dr Kanwal Sohail
Date Deposited: 09 Mar 2020 08:49
Last Modified: 09 Mar 2020 08:49
URI: http://research.riphah.edu.pk/id/eprint/277

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